BCOR_0718 protein (Bifidobacterium coryneforme)

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BCOR_0718

Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (1036 aa)

Predicted Functional Partners:

BCOR_0903

0.867

BCOR_0716

0.734

pyrB

0.734

crgA

0.716

pyrE

0.714

pyrD

0.714

BCOR_0713

0.714

pyrF

0.714

BCOR_0715

0.714

BCOR_0442

0.703

Your Current Organism:

Bifidobacterium coryneforme

NCBI taxonomy Id: 1687
Other names: AS 1.2279, ATCC 25911, B. coryneforme, BCRC 14675, Bifidobacterium sp. Bma6, CCRC 14675, CCRC:14675, CCUG 34986, DSM 20216, JCM 5819, LMG 18911, LMG:18911

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCOR_0442	BCOR_0718	BCOR_0442	BCOR_0718	Glutamine synthetase GlnA.	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	0.703
BCOR_0442	BCOR_0903	BCOR_0442	BCOR_0903	Glutamine synthetase GlnA.	Glutamine synthetase.	0.920
BCOR_0713	BCOR_0715	BCOR_0713	BCOR_0715	Dihydroorotate dehydrogenase electron transfer subunit.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	0.997
BCOR_0713	BCOR_0716	BCOR_0713	BCOR_0716	Dihydroorotate dehydrogenase electron transfer subunit.	Aspartate carbamoyltransferase PyrI.	0.869
BCOR_0713	BCOR_0718	BCOR_0713	BCOR_0718	Dihydroorotate dehydrogenase electron transfer subunit.	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	0.714
BCOR_0713	pyrB	BCOR_0713	BCOR_0717	Dihydroorotate dehydrogenase electron transfer subunit.	Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.992
BCOR_0713	pyrD	BCOR_0713	BCOR_0712	Dihydroorotate dehydrogenase electron transfer subunit.	Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.	0.999
BCOR_0713	pyrE	BCOR_0713	BCOR_0711	Dihydroorotate dehydrogenase electron transfer subunit.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.996
BCOR_0713	pyrF	BCOR_0713	BCOR_0714	Dihydroorotate dehydrogenase electron transfer subunit.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	0.966
BCOR_0715	BCOR_0713	BCOR_0715	BCOR_0713	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	Dihydroorotate dehydrogenase electron transfer subunit.	0.997
BCOR_0715	BCOR_0716	BCOR_0715	BCOR_0716	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	Aspartate carbamoyltransferase PyrI.	0.983
BCOR_0715	BCOR_0718	BCOR_0715	BCOR_0718	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	0.714
BCOR_0715	pyrB	BCOR_0715	BCOR_0717	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.999
BCOR_0715	pyrD	BCOR_0715	BCOR_0712	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.	0.999
BCOR_0715	pyrE	BCOR_0715	BCOR_0711	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.977
BCOR_0715	pyrF	BCOR_0715	BCOR_0714	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	0.977
BCOR_0716	BCOR_0713	BCOR_0716	BCOR_0713	Aspartate carbamoyltransferase PyrI.	Dihydroorotate dehydrogenase electron transfer subunit.	0.869
BCOR_0716	BCOR_0715	BCOR_0716	BCOR_0715	Aspartate carbamoyltransferase PyrI.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	0.983
BCOR_0716	BCOR_0718	BCOR_0716	BCOR_0718	Aspartate carbamoyltransferase PyrI.	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	0.734
BCOR_0716	pyrB	BCOR_0716	BCOR_0717	Aspartate carbamoyltransferase PyrI.	Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.999

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