| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCOR_0726 | metE | BCOR_0726 | BCOR_0727 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.948 |
| BCOR_0726 | metK | BCOR_0726 | BCOR_0949 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.661 |
| BCOR_0948 | ilvD | BCOR_0948 | BCOR_0951 | Primosomal protein PriA. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.505 |
| BCOR_0948 | metK | BCOR_0948 | BCOR_0949 | Primosomal protein PriA. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.652 |
| BCOR_0948 | rpoZ | BCOR_0948 | BCOR_0950 | Primosomal protein PriA. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.734 |
| BCOR_1129 | metE | BCOR_1129 | BCOR_0727 | S-adenosylhomocysteine hydrolase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.956 |
| BCOR_1129 | metK | BCOR_1129 | BCOR_0949 | S-adenosylhomocysteine hydrolase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.747 |
| guaA | ilvD | BCOR_0779 | BCOR_0951 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.430 |
| guaA | metK | BCOR_0779 | BCOR_0949 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.656 |
| guaA | purF | BCOR_0779 | BCOR_1010 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.688 |
| guaA | rsmA | BCOR_0779 | BCOR_0019 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.463 |
| ilvD | BCOR_0948 | BCOR_0951 | BCOR_0948 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Primosomal protein PriA. | 0.505 |
| ilvD | guaA | BCOR_0951 | BCOR_0779 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.430 |
| ilvD | metK | BCOR_0951 | BCOR_0949 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.656 |
| ilvD | rpoZ | BCOR_0951 | BCOR_0950 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.726 |
| metE | BCOR_0726 | BCOR_0727 | BCOR_0726 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.948 |
| metE | BCOR_1129 | BCOR_0727 | BCOR_1129 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | S-adenosylhomocysteine hydrolase. | 0.956 |
| metE | metK | BCOR_0727 | BCOR_0949 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.968 |
| metK | BCOR_0726 | BCOR_0949 | BCOR_0726 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.661 |
| metK | BCOR_0948 | BCOR_0949 | BCOR_0948 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Primosomal protein PriA. | 0.652 |
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