Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KZB65752.13-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)    
Predicted Functional Partners:
KZB64078.1
hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.912
KZB60564.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.887
KZB69481.1
Sugar dehydrogenase; Converts glucose to D-glucono-1,5 lactone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.667
KZB60563.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.662
KZB63968.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.581
KZB65753.1
RNA polymerase subunit sigma-54; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.554
KZB65792.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.536
KZB65750.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.532
KZB65751.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.532
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.487
Your Current Organism:
Thalassospira lucentensis
NCBI taxonomy Id: 168935
Other names: CECT 5390, DSM 14000, T. lucentensis, Thalassospira lucentensis Lopez-Lopez et al. 2002, strain QMT2
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