AMS29531.1 protein (Hyphomonadaceae bacterium UKL131)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AMS29531.1

Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)

Predicted Functional Partners:

AMS29532.1

0.841

AMS29530.1

0.773

AMS29928.1

0.745

AMS28923.1

0.670

AMS28517.1

0.622

AMS29265.1

0.544

Your Current Organism:

Hyphomonadaceae bacterium UKL131

NCBI taxonomy Id: 1690484
Other names: Alphaproteobacteria bacterium UKL13-1, H. bacterium UKL13-1, Hyphomonadaceae bacterium UKL13-1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMS28517.1	AMS29531.1	AEM38_01905	AEM38_08805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.622
AMS28923.1	AMS29531.1	AEM38_04665	AEM38_08805	alanyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.670
AMS29265.1	AMS29531.1	AEM38_07040	AEM38_08805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.544
AMS29530.1	AMS29531.1	AEM38_08800	AEM38_08805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
AMS29530.1	AMS29532.1	AEM38_08800	AEM38_08810	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
AMS29531.1	AMS28517.1	AEM38_08805	AEM38_01905	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.622
AMS29531.1	AMS28923.1	AEM38_08805	AEM38_04665	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	alanyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.670
AMS29531.1	AMS29265.1	AEM38_08805	AEM38_07040	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.544
AMS29531.1	AMS29530.1	AEM38_08805	AEM38_08800	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
AMS29531.1	AMS29532.1	AEM38_08805	AEM38_08810	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
AMS29531.1	AMS29928.1	AEM38_08805	AEM38_11500	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.745
AMS29532.1	AMS29530.1	AEM38_08810	AEM38_08800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
AMS29532.1	AMS29531.1	AEM38_08810	AEM38_08805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
AMS29928.1	AMS29531.1	AEM38_11500	AEM38_08805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.745

Network Stats

number of nodes:

6

number of edges:

11

average node degree:

3.67

avg. local clustering coefficient:

0.822

expected number of edges:

5

PPI enrichment p-value:

0.0149

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000724

Double-strand break repair via homologous recombination

4 of 4

2.79

4.4

1.72e-07

GO:0006310

DNA recombination

5 of 158

1.29

1.4

0.00013

GO:0016043

Cellular component organization

5 of 184

1.22

1.26

0.00022

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008854

Exodeoxyribonuclease V activity

4 of 4

2.79

4.53

1.04e-07

GO:0003678

DNA helicase activity

4 of 13

2.28

3.61

8.94e-07

GO:0004386

Helicase activity

5 of 31

2.0

3.56

1.50e-07

GO:0005524

ATP binding

5 of 361

0.93

0.74

0.0029

GO:0016787

Hydrolase activity

5 of 524

0.77

0.54

0.0104

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009338

Exodeoxyribonuclease V complex

4 of 4

2.79

4.98

1.96e-08

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:689

DNA repair, and DNA repair complex

5 of 38

1.91

3.1

8.09e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03440

Homologous recombination

4 of 45

1.74

2.17

4.87e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009338

Exodeoxyribonuclease V complex

4 of 4

2.79

4.78

4.23e-08

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0269

Exonuclease

3 of 15

2.09

2.04

0.00044

KW-0347

Helicase

3 of 24

1.89

1.79

0.00078

KW-0234

DNA repair

3 of 30

1.79

1.69

0.00096

KW-0238

DNA-binding

3 of 130

1.15

0.69

0.0318

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13538

UvrD-like helicase C-terminal domain

2 of 4

2.49

1.13

0.0201

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR027785

UvrD-like helicase C-terminal domain

3 of 3

2.79

2.73

7.47e-05

IPR014016

UvrD-like helicase, ATP-binding domain

2 of 4

2.49

1.17

0.0173

IPR011335

Restriction endonuclease type II-like

2 of 8

2.19

0.93

0.0388

IPR027417

P-loop containing nucleoside triphosphate hydrolase

5 of 230

1.13

0.9

0.0044

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (24%) [HD]

Permalink

Network

Neighborhood

Textmining

Cooccurrence

Experiments

Coexpression

Databases

Fusion

© STRING Consortium 2024

Credits

Access

Info

About