node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MetC | SEH42015.1 | SAMN05192544_1013153 | SAMN05192544_1001382 | Cystathionine beta-lyase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.931 |
MetC | SEH42027.1 | SAMN05192544_1013153 | SAMN05192544_1001383 | Cystathionine beta-lyase. | Methionine synthase (B12-dependent). | 0.952 |
MetC | SEH54711.1 | SAMN05192544_1013153 | SAMN05192544_1003284 | Cystathionine beta-lyase. | Homocysteine S-methyltransferase. | 0.926 |
MetC | SEH81661.1 | SAMN05192544_1013153 | SAMN05192544_1009115 | Cystathionine beta-lyase. | Cystathionine beta-lyase. | 0.911 |
MetC | SEH87991.1 | SAMN05192544_1013153 | SAMN05192544_101115 | Cystathionine beta-lyase. | O-acetylhomoserine sulfhydrylase. | 0.942 |
MetC | SEI18852.1 | SAMN05192544_1013153 | SAMN05192544_103313 | Cystathionine beta-lyase. | Cystathionine gamma-synthase. | 0.942 |
MetC | metE | SAMN05192544_1013153 | SAMN05192544_104535 | Cystathionine beta-lyase. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.969 |
MetC | metZ | SAMN05192544_1013153 | SAMN05192544_104838 | Cystathionine beta-lyase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.924 |
SEH42015.1 | MetC | SAMN05192544_1001382 | SAMN05192544_1013153 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase. | 0.931 |
SEH42015.1 | SEH42027.1 | SAMN05192544_1001382 | SAMN05192544_1001383 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase (B12-dependent). | 0.999 |
SEH42015.1 | SEH54711.1 | SAMN05192544_1001382 | SAMN05192544_1003284 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homocysteine S-methyltransferase. | 0.920 |
SEH42015.1 | SEH81661.1 | SAMN05192544_1001382 | SAMN05192544_1009115 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase. | 0.931 |
SEH42015.1 | SEH87991.1 | SAMN05192544_1001382 | SAMN05192544_101115 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrylase. | 0.929 |
SEH42015.1 | SEI18852.1 | SAMN05192544_1001382 | SAMN05192544_103313 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase. | 0.929 |
SEH42015.1 | SEI20415.1 | SAMN05192544_1001382 | SAMN05192544_103715 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aromatic-amino-acid transaminase. | 0.904 |
SEH42015.1 | metE | SAMN05192544_1001382 | SAMN05192544_104535 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.937 |
SEH42015.1 | metK | SAMN05192544_1001382 | SAMN05192544_1001216 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.938 |
SEH42015.1 | metZ | SAMN05192544_1001382 | SAMN05192544_104838 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.931 |
SEH42027.1 | MetC | SAMN05192544_1001383 | SAMN05192544_1013153 | Methionine synthase (B12-dependent). | Cystathionine beta-lyase. | 0.952 |
SEH42027.1 | SEH42015.1 | SAMN05192544_1001383 | SAMN05192544_1001382 | Methionine synthase (B12-dependent). | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |