node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEH68978.1 | SEH74405.1 | SAMN05192544_100671 | SAMN05192544_1007133 | Predicted metal-dependent hydrolase, TIM-barrel fold. | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | 0.542 |
SEH74367.1 | SEH74379.1 | SAMN05192544_1007130 | SAMN05192544_1007131 | Pyrroline-5-carboxylate reductase. | Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.619 |
SEH74367.1 | SEH74390.1 | SAMN05192544_1007130 | SAMN05192544_1007132 | Pyrroline-5-carboxylate reductase. | Glycine/D-amino acid oxidase. | 0.571 |
SEH74367.1 | SEH74405.1 | SAMN05192544_1007130 | SAMN05192544_1007133 | Pyrroline-5-carboxylate reductase. | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | 0.593 |
SEH74367.1 | glyA | SAMN05192544_1007130 | SAMN05192544_1007134 | Pyrroline-5-carboxylate reductase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.535 |
SEH74379.1 | SEH74367.1 | SAMN05192544_1007131 | SAMN05192544_1007130 | Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase. | 0.619 |
SEH74379.1 | SEH74390.1 | SAMN05192544_1007131 | SAMN05192544_1007132 | Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glycine/D-amino acid oxidase. | 0.783 |
SEH74379.1 | SEH74405.1 | SAMN05192544_1007131 | SAMN05192544_1007133 | Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | 0.764 |
SEH74379.1 | glyA | SAMN05192544_1007131 | SAMN05192544_1007134 | Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.631 |
SEH74390.1 | SEH74367.1 | SAMN05192544_1007132 | SAMN05192544_1007130 | Glycine/D-amino acid oxidase. | Pyrroline-5-carboxylate reductase. | 0.571 |
SEH74390.1 | SEH74379.1 | SAMN05192544_1007132 | SAMN05192544_1007131 | Glycine/D-amino acid oxidase. | Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.783 |
SEH74390.1 | SEH74405.1 | SAMN05192544_1007132 | SAMN05192544_1007133 | Glycine/D-amino acid oxidase. | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | 0.812 |
SEH74390.1 | glyA | SAMN05192544_1007132 | SAMN05192544_1007134 | Glycine/D-amino acid oxidase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.670 |
SEH74405.1 | SEH68978.1 | SAMN05192544_1007133 | SAMN05192544_100671 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Predicted metal-dependent hydrolase, TIM-barrel fold. | 0.542 |
SEH74405.1 | SEH74367.1 | SAMN05192544_1007133 | SAMN05192544_1007130 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Pyrroline-5-carboxylate reductase. | 0.593 |
SEH74405.1 | SEH74379.1 | SAMN05192544_1007133 | SAMN05192544_1007131 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.764 |
SEH74405.1 | SEH74390.1 | SAMN05192544_1007133 | SAMN05192544_1007132 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Glycine/D-amino acid oxidase. | 0.812 |
SEH74405.1 | SEH82337.1 | SAMN05192544_1007133 | SAMN05192544_1009166 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Homoserine dehydrogenase. | 0.926 |
SEH74405.1 | asd | SAMN05192544_1007133 | SAMN05192544_104850 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.940 |
SEH74405.1 | dapB | SAMN05192544_1007133 | SAMN05192544_1018107 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.984 |