STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH73553.1Propionate CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (530 aa)    
Predicted Functional Partners:
accD
acetyl-CoA carboxylase carboxyltransferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 0.933
SEI28322.1
Acyl CoA:acetate/3-ketoacid CoA transferase.
  
  
 
0.913
AceF
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
  0.912
SEH51971.1
Propionate CoA-transferase.
  
  
 
0.911
SEH68858.1
Propionate CoA-transferase.
  
  
 
0.910
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.908
SEH41825.1
Hypothetical protein.
  
 
 0.907
SEH94428.1
Phosphate acetyltransferase.
     
 0.905
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.905
SEI20526.1
acetyl-CoA synthetase.
     
 0.905
Your Current Organism:
Paraburkholderia hospita
NCBI taxonomy Id: 169430
Other names: Burkholderia hospita, Burkholderia hospita Goris et al. 2003, Burkholderia sp. LMG 20598, CCUG 43658, CCUG 43661, CIP 107793, DSM 17164, LMG 20598, LMG:20598, P. hospita, Paraburkholderia hospita (Goris et al. 2003) Sawana et al. 2015, strain Goris R-8366, strain R-8366
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