STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)    
Predicted Functional Partners:
SEI23594.1
Succinate dehydrogenase subunit A.
 0.989
sdhB
Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.976
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.976
SEH64033.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.968
SEI06392.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.968
SEI25506.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Belongs to the malic enzymes family.
  
 
 0.968
SEI20479.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.967
SEH78875.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.957
SdhC
Succinate dehydrogenase subunit C.
  
 
 0.951
SdhD
Succinate dehydrogenase subunit D.
  
 
 0.930
Your Current Organism:
Paraburkholderia hospita
NCBI taxonomy Id: 169430
Other names: Burkholderia hospita, Burkholderia hospita Goris et al. 2003, Burkholderia sp. LMG 20598, CCUG 43658, CCUG 43661, CIP 107793, DSM 17164, LMG 20598, LMG:20598, P. hospita, Paraburkholderia hospita (Goris et al. 2003) Sawana et al. 2015, strain Goris R-8366, strain R-8366
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