STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEI27473.1Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (570 aa)    
Predicted Functional Partners:
SEI27472.1
4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family.
 
 
 0.971
SEI18830.1
4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family.
 
 
 0.921
SEH49216.1
2-dehydro-3-deoxy-L-arabinonate dehydratase; Belongs to the DapA family.
 
 
 0.918
SEI06340.1
L-arabinonolactonase.
 
  
 0.918
SEH49253.1
L-arabonate dehydrase; Belongs to the IlvD/Edd family.
  
  
 
0.901
SEH52834.1
L-arabinonate dehydratase; Belongs to the IlvD/Edd family.
  
  
 
0.901
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.817
SEH85606.1
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit.
 
  
 0.813
IlvB
Acetolactate synthase, large subunit.
  
 0.779
IlvB-2
Acetolactate synthase, large subunit.
  
 0.770
Your Current Organism:
Paraburkholderia hospita
NCBI taxonomy Id: 169430
Other names: Burkholderia hospita, Burkholderia hospita Goris et al. 2003, Burkholderia sp. LMG 20598, CCUG 43658, CCUG 43661, CIP 107793, DSM 17164, LMG 20598, LMG:20598, P. hospita, Paraburkholderia hospita (Goris et al. 2003) Sawana et al. 2015, strain Goris R-8366, strain R-8366
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