STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addBATP-dependent helicase/deoxyribonuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1166 aa)    
Predicted Functional Partners:
addA
ATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase.
 
 
 0.998
lexA_3
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response).
  
 
 0.929
AQS00349.1
PD-(D/E)XK nuclease superfamily protein.
  
 
 0.896
sbcD
Nuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.690
speG
Spermidine N(1)-acetyltransferase.
       0.656
sbcC
Nuclease SbcCD subunit C.
 
  
 0.570
AQS02056.1
Cobalt-dependent inorganic pyrophosphatase.
 
    0.494
trmK
tRNA (adenine(22)-N(1))-methyltransferase.
 
     0.489
yhaM_2
3'-5' exoribonuclease YhaM.
 
     0.464
polC_1
DNA polymerase III PolC-type.
 
   
 0.454
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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