STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hacA_1Homoaconitase large subunit. (640 aa)    
Predicted Functional Partners:
icd
Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.984
hacA_2
Homoaconitase large subunit.
  
  
 
0.902
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.842
sodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.797
leuA_1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.777
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.762
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.762
rpmB
50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
   
   0.738
rpmF
50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
   0.724
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.724
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.