Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pflA_1Pyruvate formate-lyase 1-activating enzyme; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (169 aa)    
Predicted Functional Partners:
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
 
  
 0.852
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU.
   
    0.697
pflB_1
Formate acetyltransferase.
 
  
 0.672
pflB_2
Formate acetyltransferase.
 
  
 0.666
LacX
Aldose 1-epimerase.
  
  
 0.652
pflB_3
Formate acetyltransferase.
 
  
 0.631
AQR99660.1
5'-nucleotidase.
 
      0.629
adhE_1
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.608
hacA_1
Homoaconitase large subunit.
       0.567
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
     
 0.504
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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