htrB protein (Clostridium saccharobutylicum)

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second shell of interactors

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

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Score

htrB

Serine protease Do-like HtrB. (408 aa)

Predicted Functional Partners:

ftsH_2

0.842

glpK

0.763

rplT

0.719

barA_1

0.685

rplI

0.666

grpE

0.655

rpsF

0.624

ctc_1

0.618

ctc_2

0.618

AQS00455.1

0.615

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQS00455.1	htrB	CSACC_22790	CSACC_04690	Hypothetical protein.	Serine protease Do-like HtrB.	0.615
barA_1	glpK	CSACC_21950	CSACC_28290	Signal transduction histidine-protein kinase BarA.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	0.491
barA_1	grpE	CSACC_21950	CSACC_10770	Signal transduction histidine-protein kinase BarA.	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.659
barA_1	htrB	CSACC_21950	CSACC_04690	Signal transduction histidine-protein kinase BarA.	Serine protease Do-like HtrB.	0.685
ctc_1	ctc_2	CSACC_12220	CSACC_12230	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	0.938
ctc_1	htrB	CSACC_12220	CSACC_04690	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	Serine protease Do-like HtrB.	0.618
ctc_1	rplI	CSACC_12220	CSACC_45050	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	50S ribosomal protein L9; Binds to the 23S rRNA.	0.942
ctc_1	rplT	CSACC_12220	CSACC_27370	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.908
ctc_1	rpsF	CSACC_12220	CSACC_45100	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.945
ctc_2	ctc_1	CSACC_12230	CSACC_12220	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	0.938
ctc_2	htrB	CSACC_12230	CSACC_04690	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	Serine protease Do-like HtrB.	0.618
ctc_2	rplI	CSACC_12230	CSACC_45050	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	50S ribosomal protein L9; Binds to the 23S rRNA.	0.942
ctc_2	rplT	CSACC_12230	CSACC_27370	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.908
ctc_2	rpsF	CSACC_12230	CSACC_45100	General stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.945
ftsH_2	glpK	CSACC_15380	CSACC_28290	ATP-dependent zinc metalloprotease FtsH.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	0.983
ftsH_2	htrB	CSACC_15380	CSACC_04690	ATP-dependent zinc metalloprotease FtsH.	Serine protease Do-like HtrB.	0.842
glpK	barA_1	CSACC_28290	CSACC_21950	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	Signal transduction histidine-protein kinase BarA.	0.491
glpK	ftsH_2	CSACC_28290	CSACC_15380	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	ATP-dependent zinc metalloprotease FtsH.	0.983
glpK	htrB	CSACC_28290	CSACC_04690	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	Serine protease Do-like HtrB.	0.763
grpE	barA_1	CSACC_10770	CSACC_21950	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	Signal transduction histidine-protein kinase BarA.	0.659