| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SpoIIGA | SpoIIIAA | CSACC_13360 | CSACC_26950 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Hypothetical protein; Transcription termination factor Rho. | 0.627 |
| SpoIIGA | SpoIIP | CSACC_13360 | CSACC_10700 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage II sporulation protein SpoIIP. | 0.826 |
| SpoIIGA | SpoIIR | CSACC_13360 | CSACC_04860 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage II sporulation protein SpoIIR. | 0.918 |
| SpoIIGA | spo0A | CSACC_13360 | CSACC_26750 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.793 |
| SpoIIGA | spoIIAA | CSACC_13360 | CSACC_10590 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.884 |
| SpoIIGA | spoIIAB_1 | CSACC_13360 | CSACC_10600 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.931 |
| SpoIIGA | spoIIE | CSACC_13360 | CSACC_01350 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage II sporulation protein E. | 0.953 |
| SpoIIGA | spoIIID | CSACC_13360 | CSACC_05170 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage III sporulation protein D. | 0.743 |
| SpoIIGA | spoIVA | CSACC_13360 | CSACC_13520 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.663 |
| SpoIIGA | spoVT_1 | CSACC_13360 | CSACC_01160 | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage V sporulation protein T. | 0.586 |
| SpoIIIAA | SpoIIGA | CSACC_26950 | CSACC_13360 | Hypothetical protein; Transcription termination factor Rho. | Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.627 |
| SpoIIIAA | SpoIIP | CSACC_26950 | CSACC_10700 | Hypothetical protein; Transcription termination factor Rho. | Stage II sporulation protein SpoIIP. | 0.823 |
| SpoIIIAA | SpoIIR | CSACC_26950 | CSACC_04860 | Hypothetical protein; Transcription termination factor Rho. | Stage II sporulation protein SpoIIR. | 0.851 |
| SpoIIIAA | spo0A | CSACC_26950 | CSACC_26750 | Hypothetical protein; Transcription termination factor Rho. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.819 |
| SpoIIIAA | spoIIAA | CSACC_26950 | CSACC_10590 | Hypothetical protein; Transcription termination factor Rho. | Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.673 |
| SpoIIIAA | spoIIAB_1 | CSACC_26950 | CSACC_10600 | Hypothetical protein; Transcription termination factor Rho. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.808 |
| SpoIIIAA | spoIIE | CSACC_26950 | CSACC_01350 | Hypothetical protein; Transcription termination factor Rho. | Stage II sporulation protein E. | 0.833 |
| SpoIIIAA | spoIIID | CSACC_26950 | CSACC_05170 | Hypothetical protein; Transcription termination factor Rho. | Stage III sporulation protein D. | 0.862 |
| SpoIIIAA | spoIVA | CSACC_26950 | CSACC_13520 | Hypothetical protein; Transcription termination factor Rho. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.897 |
| SpoIIIAA | spoVT_1 | CSACC_26950 | CSACC_01160 | Hypothetical protein; Transcription termination factor Rho. | Stage V sporulation protein T. | 0.833 |