Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
thlAacetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)    
Predicted Functional Partners:
mmgB
Putative 3-hydroxybutyryl-CoA dehydrogenase.
 0.999
acdA_1
acyl-CoA dehydrogenase.
 
 0.983
echA8_1
Putative enoyl-CoA hydratase echA8; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.981
acdA_3
acyl-CoA dehydrogenase.
 
 0.976
echA8_2
Putative enoyl-CoA hydratase echA8; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.974
ctfB
Butyrate--acetoacetate CoA-transferase subunit B.
 
 
 0.971
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.955
ctfA
Butyrate--acetoacetate CoA-transferase subunit A.
 
 
 0.955
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.955
adhE_1
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.954
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
Server load: low (12%) [HD]