Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
lacSLactose permease. (463 aa)    
Predicted Functional Partners:
cbgA
Beta-galactosidase.
 
 
 0.742
crr_2
Glucose-specific phosphotransferase enzyme IIA component.
 
    
 0.629
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.598
rafA
Alpha-galactosidase.
 
  
 0.570
galT
Galactose-1-phosphate uridylyltransferase.
 
  
 0.466
fruA_3
PTS system fructose-specific EIIABC component.
  
  
 0.441
fucK
L-fuculokinase.
 
  
 0.427
ypdA_1
Sensor histidine kinase YpdA.
     
 0.418
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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