ilvB_2 protein (Clostridium saccharobutylicum)

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ilvB_2

Acetolactate synthase isozyme 1 large subunit. (377 aa)

Predicted Functional Partners:

pphA

0.996

phnW

0.985

ilvH

0.858

ilvN

0.858

spsI_1

0.809

ilvC_1

0.737

nifJ_1

0.709

nifJ_2

0.709

ilvD

0.632

tdcB

0.625

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ilvB_2	ilvC_1	CSACC_08650	CSACC_02740	Acetolactate synthase isozyme 1 large subunit.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.737
ilvB_2	ilvD	CSACC_08650	CSACC_02720	Acetolactate synthase isozyme 1 large subunit.	Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.	0.632
ilvB_2	ilvH	CSACC_08650	CSACC_02670	Acetolactate synthase isozyme 1 large subunit.	Acetolactate synthase small subunit.	0.858
ilvB_2	ilvN	CSACC_08650	CSACC_17290	Acetolactate synthase isozyme 1 large subunit.	Acetolactate synthase isozyme 1 small subunit.	0.858
ilvB_2	nifJ_1	CSACC_08650	CSACC_22230	Acetolactate synthase isozyme 1 large subunit.	Pyruvate-flavodoxin oxidoreductase.	0.709
ilvB_2	nifJ_2	CSACC_08650	CSACC_39670	Acetolactate synthase isozyme 1 large subunit.	Pyruvate-flavodoxin oxidoreductase.	0.709
ilvB_2	phnW	CSACC_08650	CSACC_08660	Acetolactate synthase isozyme 1 large subunit.	2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.	0.985
ilvB_2	pphA	CSACC_08650	CSACC_08640	Acetolactate synthase isozyme 1 large subunit.	Phosphonopyruvate hydrolase.	0.996
ilvB_2	spsI_1	CSACC_08650	CSACC_08630	Acetolactate synthase isozyme 1 large subunit.	Bifunctional IPC transferase and DIPP synthase.	0.809
ilvB_2	tdcB	CSACC_08650	CSACC_28170	Acetolactate synthase isozyme 1 large subunit.	L-threonine dehydratase catabolic TdcB.	0.625
ilvC_1	ilvB_2	CSACC_02740	CSACC_08650	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Acetolactate synthase isozyme 1 large subunit.	0.737
ilvC_1	ilvD	CSACC_02740	CSACC_02720	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.	0.999
ilvC_1	ilvH	CSACC_02740	CSACC_02670	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Acetolactate synthase small subunit.	0.999
ilvC_1	ilvN	CSACC_02740	CSACC_17290	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Acetolactate synthase isozyme 1 small subunit.	0.984
ilvC_1	nifJ_1	CSACC_02740	CSACC_22230	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Pyruvate-flavodoxin oxidoreductase.	0.554
ilvC_1	nifJ_2	CSACC_02740	CSACC_39670	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Pyruvate-flavodoxin oxidoreductase.	0.554
ilvC_1	tdcB	CSACC_02740	CSACC_28170	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	L-threonine dehydratase catabolic TdcB.	0.816
ilvD	ilvB_2	CSACC_02720	CSACC_08650	Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.	Acetolactate synthase isozyme 1 large subunit.	0.632
ilvD	ilvC_1	CSACC_02720	CSACC_02740	Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.999
ilvD	ilvH	CSACC_02720	CSACC_02670	Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.	Acetolactate synthase small subunit.	0.974