Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nagAN-acetylglucosamine-6-phosphate deacetylase. (376 aa)    
Predicted Functional Partners:
nagB
Glucosamine-6-phosphate deaminase 1; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
 0.999
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
  
 0.945
glmS
Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.942
crr_1
Glucose-specific phosphotransferase enzyme IIA component.
 
  
 0.941
crr_2
Glucose-specific phosphotransferase enzyme IIA component.
 
  
 0.940
yvoA
HTH-type transcriptional repressor YvoA.
 
  
 0.902
fruA_3
PTS system fructose-specific EIIABC component.
     
 0.700
ptsG_1
PTS system glucose-specific EIICBA component.
 
   
 0.697
AQR98731.1
DNA utilization protein GntX.
  
    0.691
bglF
PTS system beta-glucoside-specific EIIBCA component.
     
 0.633
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
Server load: low (18%) [HD]