STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cfiB_12-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1165 aa)    
Predicted Functional Partners:
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 0.972
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
  
 
 0.961
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
    
 0.961
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
    
 0.961
pyk_1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.959
pyk_2
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.959
pckA_2
Phosphoenolpyruvate carboxykinase.
    
 0.957
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.952
ldh1
L-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.952
ldhB
L-lactate dehydrogenase 2; Catalyzes the conversion of lactate to pyruvate.
  
 0.952
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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