Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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cfiB_12-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1165 aa)    
Predicted Functional Partners:
pyk_1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.965
pyk_2
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.965
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
    
 0.952
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
    
 0.952
YtsJ1
NAD-dependent malic enzyme.
   
 0.951
YtsJ2
NAD-dependent malic enzyme.
   
 0.951
ttuE
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.950
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.945
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 0.941
pckA_2
Phosphoenolpyruvate carboxykinase.
    
 0.939
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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