STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dgtDeoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (342 aa)    
Predicted Functional Partners:
surE
5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
  
 0.926
punA
Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.903
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
  0.902
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
    
  0.901
pyk_1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.901
yfkN
Trifunctional nucleotide phosphoesterase protein YfkN precursor.
    
  0.901
pyk_2
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.901
ttuE
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.900
deoD
Purine nucleoside phosphorylase DeoD-type.
     
 0.900
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
 0.693
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.