| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folP | pabA_1 | CSACC_02600 | CSACC_11250 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Aminodeoxychorismate/anthranilate synthase component 2. | 0.662 |
| folP | pabA_2 | CSACC_02600 | CSACC_23620 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Aminodeoxychorismate synthase component 2. | 0.731 |
| folP | pabB | CSACC_02600 | CSACC_11260 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Aminodeoxychorismate synthase component 1. | 0.650 |
| folP | pabC | CSACC_02600 | CSACC_11270 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Aminodeoxychorismate lyase. | 0.974 |
| folP | sulD | CSACC_02600 | CSACC_02610 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| hisI | ilvD | CSACC_31160 | CSACC_02720 | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.615 |
| hisI | ilvE_2 | CSACC_31160 | CSACC_39630 | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Branched-chain-amino-acid aminotransferase. | 0.611 |
| hisI | leuA_1 | CSACC_31160 | CSACC_00870 | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.484 |
| hisI | leuA_2 | CSACC_31160 | CSACC_02680 | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.484 |
| hisI | pabA_1 | CSACC_31160 | CSACC_11250 | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Aminodeoxychorismate/anthranilate synthase component 2. | 0.490 |
| hisI | pabA_2 | CSACC_31160 | CSACC_23620 | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Aminodeoxychorismate synthase component 2. | 0.490 |
| hisI | pabC | CSACC_31160 | CSACC_11270 | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Aminodeoxychorismate lyase. | 0.611 |
| ilvD | hisI | CSACC_02720 | CSACC_31160 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.615 |
| ilvD | ilvE_2 | CSACC_02720 | CSACC_39630 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Branched-chain-amino-acid aminotransferase. | 0.976 |
| ilvD | leuA_1 | CSACC_02720 | CSACC_00870 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.896 |
| ilvD | leuA_2 | CSACC_02720 | CSACC_02680 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.992 |
| ilvD | pabC | CSACC_02720 | CSACC_11270 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Aminodeoxychorismate lyase. | 0.840 |
| ilvE_2 | hisI | CSACC_39630 | CSACC_31160 | Branched-chain-amino-acid aminotransferase. | Histidine biosynthesis bifunctional protein HisIE; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.611 |
| ilvE_2 | ilvD | CSACC_39630 | CSACC_02720 | Branched-chain-amino-acid aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.976 |
| ilvE_2 | leuA_1 | CSACC_39630 | CSACC_00870 | Branched-chain-amino-acid aminotransferase. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.559 |