STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflA_2Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (235 aa)    
Predicted Functional Partners:
pflB_2
Formate acetyltransferase.
  
 0.939
pflB_1
Formate acetyltransferase.
  
 0.934
pflB_3
Formate acetyltransferase.
  
 0.912
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU.
   
    0.828
adhE_1
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.613
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
     
 0.609
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
     
 0.609
crp_1
cAMP receptor protein.
    
 0.496
crp_2
cAMP receptor protein.
    
 0.424
adhE_2
Aldehyde-alcohol dehydrogenase; This enzyme has activity using butanol and ethanol as substrates.
  
  
 0.416
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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