queE_1 protein (Clostridium saccharobutylicum)

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queE_1

7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (222 aa)

Predicted Functional Partners:

QueD

0.999

queC

0.998

queF

0.988

folE

0.955

nrdE2

0.925

nrdD

0.823

guaA

0.681

purL

0.512

rlmH

0.490

puuB

0.481

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
QueD	folE	CSACC_15570	CSACC_15590	6-pyruvoyl tetrahydropterin synthase.	GTP cyclohydrolase 1.	0.997
QueD	guaA	CSACC_15570	CSACC_03630	6-pyruvoyl tetrahydropterin synthase.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.510
QueD	queC	CSACC_15570	CSACC_15600	6-pyruvoyl tetrahydropterin synthase.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).	0.977
QueD	queE_1	CSACC_15570	CSACC_15580	6-pyruvoyl tetrahydropterin synthase.	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.999
QueD	queF	CSACC_15570	CSACC_15610	6-pyruvoyl tetrahydropterin synthase.	NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.	0.941
folE	QueD	CSACC_15590	CSACC_15570	GTP cyclohydrolase 1.	6-pyruvoyl tetrahydropterin synthase.	0.997
folE	guaA	CSACC_15590	CSACC_03630	GTP cyclohydrolase 1.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.514
folE	nrdD	CSACC_15590	CSACC_00860	GTP cyclohydrolase 1.	Anaerobic ribonucleoside-triphosphate reductase.	0.802
folE	queC	CSACC_15590	CSACC_15600	GTP cyclohydrolase 1.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).	0.777
folE	queE_1	CSACC_15590	CSACC_15580	GTP cyclohydrolase 1.	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.955
folE	queF	CSACC_15590	CSACC_15610	GTP cyclohydrolase 1.	NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.	0.760
guaA	QueD	CSACC_03630	CSACC_15570	GMP synthase; Catalyzes the synthesis of GMP from XMP.	6-pyruvoyl tetrahydropterin synthase.	0.510
guaA	folE	CSACC_03630	CSACC_15590	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GTP cyclohydrolase 1.	0.514
guaA	nrdE2	CSACC_03630	CSACC_02460	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribonucleoside-diphosphate reductase subunit alpha 2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.762
guaA	purL	CSACC_03630	CSACC_12910	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine synthase.	0.992
guaA	puuB	CSACC_03630	CSACC_30320	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Gamma-glutamylputrescine oxidoreductase.	0.432
guaA	queC	CSACC_03630	CSACC_15600	GMP synthase; Catalyzes the synthesis of GMP from XMP.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).	0.503
guaA	queE_1	CSACC_03630	CSACC_15580	GMP synthase; Catalyzes the synthesis of GMP from XMP.	7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.681
guaA	queF	CSACC_03630	CSACC_15610	GMP synthase; Catalyzes the synthesis of GMP from XMP.	NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.	0.646
nrdD	folE	CSACC_00860	CSACC_15590	Anaerobic ribonucleoside-triphosphate reductase.	GTP cyclohydrolase 1.	0.802

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