Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsAArsenical pump-driving ATPase. (581 aa)    
Predicted Functional Partners:
arsD
Arsenical resistance operon trans-acting repressor ArsD.
 
   
 0.953
arsC1
Arsenate-mycothiol transferase ArsC1.
   
 0.929
ArsB
Sodium bile acid symporter family protein.
     
 0.876
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
 
 0.772
arsC
Glutaredoxin arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
   
 0.741
sdpR_1
Transcriptional repressor SdpR.
 
   
 0.711
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
    
 
 0.648
AQS00652.1
Putative calcium/sodium:proton antiporter.
   
   0.610
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
   0.603
AQS00781.1
Hypothetical protein.
  
 
 0.581
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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