mbtI protein (Clostridium saccharobutylicum)

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Score

mbtI

Isochorismate synthase/isochorismate lyase. (448 aa)

Predicted Functional Partners:

pabA_2

0.993

trpD

0.972

pabA_1

0.971

trpC

0.970

dhbE

0.959

trpA

0.917

trpF

0.914

trpB

0.907

pheA

0.891

aroC

0.889

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aroC	mbtI	CSACC_06810	CSACC_16890	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Isochorismate synthase/isochorismate lyase.	0.889
aroC	pabA_1	CSACC_06810	CSACC_11250	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Aminodeoxychorismate/anthranilate synthase component 2.	0.888
aroC	pabA_2	CSACC_06810	CSACC_23620	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Aminodeoxychorismate synthase component 2.	0.950
aroC	pheA	CSACC_06810	CSACC_06820	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	P-protein.	0.998
aroC	trpA	CSACC_06810	CSACC_23570	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.759
aroC	trpB	CSACC_06810	CSACC_23580	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.658
aroC	trpC	CSACC_06810	CSACC_23600	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.	0.474
aroC	trpD	CSACC_06810	CSACC_23610	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.597
aroC	trpF	CSACC_06810	CSACC_23590	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.	0.404
dhbE	mbtI	CSACC_16930	CSACC_16890	2,3-dihydroxybenzoate-AMP ligase.	Isochorismate synthase/isochorismate lyase.	0.959
dhbE	pabA_1	CSACC_16930	CSACC_11250	2,3-dihydroxybenzoate-AMP ligase.	Aminodeoxychorismate/anthranilate synthase component 2.	0.873
dhbE	pabA_2	CSACC_16930	CSACC_23620	2,3-dihydroxybenzoate-AMP ligase.	Aminodeoxychorismate synthase component 2.	0.873
dhbE	pheA	CSACC_16930	CSACC_06820	2,3-dihydroxybenzoate-AMP ligase.	P-protein.	0.853
dhbE	trpA	CSACC_16930	CSACC_23570	2,3-dihydroxybenzoate-AMP ligase.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.683
dhbE	trpB	CSACC_16930	CSACC_23580	2,3-dihydroxybenzoate-AMP ligase.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.720
dhbE	trpC	CSACC_16930	CSACC_23600	2,3-dihydroxybenzoate-AMP ligase.	Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.	0.880
dhbE	trpD	CSACC_16930	CSACC_23610	2,3-dihydroxybenzoate-AMP ligase.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.892
dhbE	trpF	CSACC_16930	CSACC_23590	2,3-dihydroxybenzoate-AMP ligase.	N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.	0.697
mbtI	aroC	CSACC_16890	CSACC_06810	Isochorismate synthase/isochorismate lyase.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.889
mbtI	dhbE	CSACC_16890	CSACC_16930	Isochorismate synthase/isochorismate lyase.	2,3-dihydroxybenzoate-AMP ligase.	0.959