STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgrD_2Linear gramicidin synthase subunit D. (486 aa)    
Predicted Functional Partners:
mbtB_2
Phenyloxazoline synthase MbtB.
 
 0.999
grsB_2
Gramicidin S synthase 2.
 
 0.999
srfAA
Surfactin synthase subunit 1.
 
 0.999
mbtB_1
Phenyloxazoline synthase MbtB.
 
 0.998
tycC
Tyrocidine synthase 3.
 
 
0.997
grsB_1
Gramicidin S synthase 2.
 
 0.996
ppsD
Plipastatin synthase subunit D.
 
 
 0.989
dhbE
2,3-dihydroxybenzoate-AMP ligase.
  
 0.981
dltA
D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
 
 0.981
lgrE
Linear gramicidin dehydrogenase LgrE.
 
  
 0.980
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.