STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
larCHypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (439 aa)    
Predicted Functional Partners:
tilS_2
tRNA(Ile)-lysidine synthase.
 
 0.990
AQR99957.1
AIR carboxylase.
 
  
 0.962
AQS00332.1
Hypothetical protein.
 
  
 0.773
AQS00691.1
Hypothetical protein.
 
  
 0.739
nikQ
Nickel transport protein NikQ.
 
    0.723
nikO
Nickel import ATP-binding protein NikO.
  
    0.693
nikMN
Fused nickel transport protein NikMN.
 
    0.679
rsxB_4
Electron transport complex subunit RsxB.
 
    0.503
cbiM
Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.464
cinA_2
Putative competence-damage inducible protein; Belongs to the CinA family.
       0.448
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.