STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exuRPutative HTH-type transcriptional repressor ExuR. (334 aa)    
Predicted Functional Partners:
tycC
Tyrocidine synthase 3.
    
 
 0.655
srfAA
Surfactin synthase subunit 1.
    
 
 0.655
ptsH
Phosphocarrier protein HPr.
   
 
 0.642
uxaC
Uronate isomerase.
 
  
 0.630
pyk_1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.620
pyk_2
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.620
trxB_1
Thioredoxin reductase.
  
 
 0.610
grsB_2
Gramicidin S synthase 2.
    
 
 0.595
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.594
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
   0.587
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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