Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pitALow-affinity inorganic phosphate transporter 1. (334 aa)    
Predicted Functional Partners:
YkaA
Putative pit accessory protein.
 
  
 0.993
yflS
Putative malate transporter YflS.
   
 
 0.556
lysS
lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.520
nasF
uroporphyrinogen-III C-methyltransferase.
  
  
 0.517
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
    0.505
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
   0.499
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
     
 0.481
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
     
 0.481
pstB3
Phosphate import ATP-binding protein PstB 3; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.473
tdcB
L-threonine dehydratase catabolic TdcB.
   
 
 0.463
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
Server load: low (12%) [HD]