| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CbiJ | cbiH | CSACC_32000 | CSACC_32010 | Cobalt-precorrin-6x reductase. | cobalt-precorrin-3B C(17)-methyltransferase. | 0.999 |
| CbiJ | cbiL | CSACC_32000 | CSACC_32310 | Cobalt-precorrin-6x reductase. | Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | 0.993 |
| CbiJ | cobQ_2 | CSACC_32000 | CSACC_31820 | Cobalt-precorrin-6x reductase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.993 |
| CbiJ | cobS | CSACC_32000 | CSACC_31880 | Cobalt-precorrin-6x reductase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.950 |
| CbiJ | cobT | CSACC_32000 | CSACC_31960 | Cobalt-precorrin-6x reductase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.815 |
| CbiJ | cobU | CSACC_32000 | CSACC_31890 | Cobalt-precorrin-6x reductase. | Bifunctional adenosylcobalamin biosynthesis protein CobU. | 0.713 |
| CbiJ | pspB_1 | CSACC_32000 | CSACC_25280 | Cobalt-precorrin-6x reductase. | Putative phosphoserine phosphatase 2; Belongs to the phosphoglycerate mutase family. | 0.486 |
| cbiH | CbiJ | CSACC_32010 | CSACC_32000 | cobalt-precorrin-3B C(17)-methyltransferase. | Cobalt-precorrin-6x reductase. | 0.999 |
| cbiH | cbiL | CSACC_32010 | CSACC_32310 | cobalt-precorrin-3B C(17)-methyltransferase. | Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | 0.992 |
| cbiH | cobQ_2 | CSACC_32010 | CSACC_31820 | cobalt-precorrin-3B C(17)-methyltransferase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.996 |
| cbiH | cobS | CSACC_32010 | CSACC_31880 | cobalt-precorrin-3B C(17)-methyltransferase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.995 |
| cbiH | cobT | CSACC_32010 | CSACC_31960 | cobalt-precorrin-3B C(17)-methyltransferase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.904 |
| cbiH | cobU | CSACC_32010 | CSACC_31890 | cobalt-precorrin-3B C(17)-methyltransferase. | Bifunctional adenosylcobalamin biosynthesis protein CobU. | 0.811 |
| cbiH | pspB_1 | CSACC_32010 | CSACC_25280 | cobalt-precorrin-3B C(17)-methyltransferase. | Putative phosphoserine phosphatase 2; Belongs to the phosphoglycerate mutase family. | 0.467 |
| cbiL | CbiJ | CSACC_32310 | CSACC_32000 | Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Cobalt-precorrin-6x reductase. | 0.993 |
| cbiL | cbiH | CSACC_32310 | CSACC_32010 | Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | cobalt-precorrin-3B C(17)-methyltransferase. | 0.992 |
| cbiL | cobQ_2 | CSACC_32310 | CSACC_31820 | Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.994 |
| cbiL | cobS | CSACC_32310 | CSACC_31880 | Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.928 |
| cbiL | cobT | CSACC_32310 | CSACC_31960 | Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.932 |
| cbiL | cobU | CSACC_32310 | CSACC_31890 | Cobalt-precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Bifunctional adenosylcobalamin biosynthesis protein CobU. | 0.823 |