nit protein (Clostridium saccharobutylicum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nit

Nitrilase. (327 aa)

Predicted Functional Partners:

AQR99845.1

0.582

barA_1

0.568

cocE

0.552

guaA

0.490

cynR_3

0.451

puuE

0.447

purL

0.444

todS_6

0.429

pheA

0.410

pstB3

0.408

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR99845.1	cocE	CSACC_16540	CSACC_11840	Tannase and feruloyl esterase.	Cocaine esterase.	0.643
AQR99845.1	nit	CSACC_16540	CSACC_25300	Tannase and feruloyl esterase.	Nitrilase.	0.582
barA_1	guaA	CSACC_21950	CSACC_03630	Signal transduction histidine-protein kinase BarA.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.640
barA_1	nit	CSACC_21950	CSACC_25300	Signal transduction histidine-protein kinase BarA.	Nitrilase.	0.568
barA_1	pheA	CSACC_21950	CSACC_06820	Signal transduction histidine-protein kinase BarA.	P-protein.	0.763
barA_1	pstB3	CSACC_21950	CSACC_13470	Signal transduction histidine-protein kinase BarA.	Phosphate import ATP-binding protein PstB 3; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.	0.522
barA_1	purL	CSACC_21950	CSACC_12910	Signal transduction histidine-protein kinase BarA.	Phosphoribosylformylglycinamidine synthase.	0.673
barA_1	todS_6	CSACC_21950	CSACC_37270	Signal transduction histidine-protein kinase BarA.	Sensor histidine kinase TodS.	0.974
cocE	AQR99845.1	CSACC_11840	CSACC_16540	Cocaine esterase.	Tannase and feruloyl esterase.	0.643
cocE	nit	CSACC_11840	CSACC_25300	Cocaine esterase.	Nitrilase.	0.552
cynR_3	nit	CSACC_25310	CSACC_25300	HTH-type transcriptional regulator CynR; Belongs to the LysR transcriptional regulatory family.	Nitrilase.	0.451
guaA	barA_1	CSACC_03630	CSACC_21950	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Signal transduction histidine-protein kinase BarA.	0.640
guaA	nit	CSACC_03630	CSACC_25300	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Nitrilase.	0.490
guaA	pheA	CSACC_03630	CSACC_06820	GMP synthase; Catalyzes the synthesis of GMP from XMP.	P-protein.	0.804
guaA	pstB3	CSACC_03630	CSACC_13470	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphate import ATP-binding protein PstB 3; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.	0.674
guaA	purL	CSACC_03630	CSACC_12910	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine synthase.	0.992
guaA	puuE	CSACC_03630	CSACC_08530	GMP synthase; Catalyzes the synthesis of GMP from XMP.	4-aminobutyrate aminotransferase PuuE; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.538
guaA	todS_6	CSACC_03630	CSACC_37270	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Sensor histidine kinase TodS.	0.559
nit	AQR99845.1	CSACC_25300	CSACC_16540	Nitrilase.	Tannase and feruloyl esterase.	0.582
nit	barA_1	CSACC_25300	CSACC_21950	Nitrilase.	Signal transduction histidine-protein kinase BarA.	0.568