relA protein (Clostridium saccharobutylicum)

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relA

GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (736 aa)

Predicted Functional Partners:

gmk

0.928

pyk_1

0.923

ndk

0.922

yjbM

0.919

nrdE2

0.913

pyk_2

0.913

rpsF

0.908

ttuE

0.905

nrdD

0.903

nrdB

0.902

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gmk	ndk	CSACC_13570	CSACC_11290	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.934
gmk	nrdB	CSACC_13570	CSACC_02470	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.910
gmk	nrdE2	CSACC_13570	CSACC_02460	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonucleoside-diphosphate reductase subunit alpha 2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.932
gmk	pyk_1	CSACC_13570	CSACC_06040	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.931
gmk	pyk_2	CSACC_13570	CSACC_42620	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.931
gmk	relA	CSACC_13570	CSACC_28680	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.928
gmk	ttuE	CSACC_13570	CSACC_30500	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.915
ndk	gmk	CSACC_11290	CSACC_13570	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.934
ndk	nrdB	CSACC_11290	CSACC_02470	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.917
ndk	nrdD	CSACC_11290	CSACC_00860	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Anaerobic ribonucleoside-triphosphate reductase.	0.910
ndk	nrdE2	CSACC_11290	CSACC_02460	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Ribonucleoside-diphosphate reductase subunit alpha 2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.940
ndk	pyk_1	CSACC_11290	CSACC_06040	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.908
ndk	pyk_2	CSACC_11290	CSACC_42620	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.908
ndk	relA	CSACC_11290	CSACC_28680	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.922
ndk	rpsF	CSACC_11290	CSACC_45100	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.990
ndk	ttuE	CSACC_11290	CSACC_30500	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.908
ndk	yjbM	CSACC_11290	CSACC_40790	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	GTP pyrophosphokinase YjbM.	0.900
nrdB	gmk	CSACC_02470	CSACC_13570	Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.910
nrdB	ndk	CSACC_02470	CSACC_11290	Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.917
nrdB	nrdD	CSACC_02470	CSACC_00860	Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	Anaerobic ribonucleoside-triphosphate reductase.	0.590

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