Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
merR1_2Mercuric resistance operon regulatory protein. (146 aa)    
Predicted Functional Partners:
adhR_2
HTH-type transcriptional regulator AdhR.
  
   
 0.712
adhR_1
HTH-type transcriptional regulator AdhR.
  
   
 0.666
AQS01602.1
Hypothetical protein.
       0.661
barA_1
Signal transduction histidine-protein kinase BarA.
   
 
 0.635
bmrR_2
Multidrug-efflux transporter 1 regulator.
  
   
 0.621
glnA_1
Glutamine synthetase; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under [...]
  
 
 0.602
bmrR_1
Multidrug-efflux transporter 1 regulator.
  
   
 0.576
AQS00084.1
Putative histidine kinase sensor domain protein.
   
 
 0.553
sigA
RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.538
todS_6
Sensor histidine kinase TodS.
  
 
 0.523
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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