STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YtsJ2NAD-dependent malic enzyme. (404 aa)    
Predicted Functional Partners:
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.960
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.960
pyk_1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.952
pyk_2
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.952
cfiB_1
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.944
fumB
Fumarate hydratase class I, anaerobic.
 
 
 0.943
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.935
ldh1
L-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.935
ldhB
L-lactate dehydrogenase 2; Catalyzes the conversion of lactate to pyruvate.
  
 0.935
ttuE
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.930
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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