STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pckA_2Phosphoenolpyruvate carboxykinase. (522 aa)    
Predicted Functional Partners:
cfiB_1
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.957
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.948
pyk_1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.927
pyk_2
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.927
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.920
ttuE
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.907
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.895
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.895
aspA_1
Aspartate ammonia-lyase.
  
 
 0.883
aspA_2
Aspartate ammonia-lyase.
  
 
 0.883
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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