clpA protein (Clostridium saccharobutylicum)

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clpA

ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (762 aa)

Predicted Functional Partners:

clpS

0.985

clpP

0.892

tepA

0.827

Hsp

0.826

grpE

0.806

AQS02580.1

0.787

mcsB

0.780

dnaK_1

0.759

dnaK_2

0.759

dnaK_3

0.759

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQS02580.1	clpA	CSACC_44370	CSACC_38540	Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family.	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	0.787
AQS02580.1	dnaK_1	CSACC_44370	CSACC_06640	Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.465
AQS02580.1	dnaK_2	CSACC_44370	CSACC_06650	Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.465
AQS02580.1	dnaK_3	CSACC_44370	CSACC_06670	Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein DnaK.	0.465
AQS02580.1	grpE	CSACC_44370	CSACC_10770	Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family.	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.582
Hsp	clpA	CSACC_02650	CSACC_38540	18 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family.	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	0.826
Hsp	dnaK_1	CSACC_02650	CSACC_06640	18 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.509
Hsp	dnaK_2	CSACC_02650	CSACC_06650	18 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.509
Hsp	dnaK_3	CSACC_02650	CSACC_06670	18 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein DnaK.	0.509
Hsp	grpE	CSACC_02650	CSACC_10770	18 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.681
clpA	AQS02580.1	CSACC_38540	CSACC_44370	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family.	0.787
clpA	Hsp	CSACC_38540	CSACC_02650	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	18 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family.	0.826
clpA	clpP	CSACC_38540	CSACC_31110	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.892
clpA	clpS	CSACC_38540	CSACC_38550	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.	0.985
clpA	dnaK_1	CSACC_38540	CSACC_06640	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.759
clpA	dnaK_2	CSACC_38540	CSACC_06650	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.759
clpA	dnaK_3	CSACC_38540	CSACC_06670	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Chaperone protein DnaK.	0.759
clpA	grpE	CSACC_38540	CSACC_10770	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.806
clpA	mcsB	CSACC_38540	CSACC_01700	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Putative ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family.	0.780
clpA	tepA	CSACC_38540	CSACC_14460	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Translocation-enhancing protein TepA.	0.827