ltaE protein (Clostridium saccharobutylicum)

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Score

ltaE

Low specificity L-threonine aldolase. (369 aa)

Predicted Functional Partners:

glyA

0.957

tdcB

0.942

thrC

0.937

AQR99718.1

0.900

AQS02025.1

0.515

AQS02056.1

0.486

guaB

0.472

speA_2

0.464

tycC

0.426

srfAA

0.426

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR99718.1	glyA	CSACC_15270	CSACC_27930	Glycine/sarcosine N-methyltransferase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.920
AQR99718.1	ltaE	CSACC_15270	CSACC_38570	Glycine/sarcosine N-methyltransferase.	Low specificity L-threonine aldolase.	0.900
AQS02025.1	ltaE	CSACC_38580	CSACC_38570	Insulinase.	Low specificity L-threonine aldolase.	0.515
AQS02056.1	guaB	CSACC_38890	CSACC_03620	Cobalt-dependent inorganic pyrophosphatase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.745
AQS02056.1	ltaE	CSACC_38890	CSACC_38570	Cobalt-dependent inorganic pyrophosphatase.	Low specificity L-threonine aldolase.	0.486
glyA	AQR99718.1	CSACC_27930	CSACC_15270	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glycine/sarcosine N-methyltransferase.	0.920
glyA	guaB	CSACC_27930	CSACC_03620	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.745
glyA	ltaE	CSACC_27930	CSACC_38570	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Low specificity L-threonine aldolase.	0.957
glyA	tdcB	CSACC_27930	CSACC_28170	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-threonine dehydratase catabolic TdcB.	0.938
guaB	AQS02056.1	CSACC_03620	CSACC_38890	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Cobalt-dependent inorganic pyrophosphatase.	0.745
guaB	glyA	CSACC_03620	CSACC_27930	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.745
guaB	ltaE	CSACC_03620	CSACC_38570	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Low specificity L-threonine aldolase.	0.472
guaB	thrC	CSACC_03620	CSACC_31400	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Threonine synthase.	0.695
ltaE	AQR99718.1	CSACC_38570	CSACC_15270	Low specificity L-threonine aldolase.	Glycine/sarcosine N-methyltransferase.	0.900
ltaE	AQS02025.1	CSACC_38570	CSACC_38580	Low specificity L-threonine aldolase.	Insulinase.	0.515
ltaE	AQS02056.1	CSACC_38570	CSACC_38890	Low specificity L-threonine aldolase.	Cobalt-dependent inorganic pyrophosphatase.	0.486
ltaE	glyA	CSACC_38570	CSACC_27930	Low specificity L-threonine aldolase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.957
ltaE	guaB	CSACC_38570	CSACC_03620	Low specificity L-threonine aldolase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.472
ltaE	speA_2	CSACC_38570	CSACC_38560	Low specificity L-threonine aldolase.	Arginine decarboxylase.	0.464
ltaE	srfAA	CSACC_38570	CSACC_37480	Low specificity L-threonine aldolase.	Surfactin synthase subunit 1.	0.426