parE protein (Clostridium saccharobutylicum)

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[Homology]

Score

parE

DNA topoisomerase 4 subunit B. (649 aa)

Predicted Functional Partners:

gyrA_2

0.995

gyrA_1

0.990

truB

0.722

dnaN

0.697

dnaK_1

0.679

recF_1

0.669

dnaK_2

0.667

dnaK_4

0.640

smc_3

0.633

AQR99722.1

0.633

Your Current Organism:

Clostridium saccharobutylicum

NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR99722.1	parE	CSACC_15310	CSACC_39730	Hypothetical protein.	DNA topoisomerase 4 subunit B.	0.633
dnaK_1	dnaK_2	CSACC_06640	CSACC_06650	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.821
dnaK_1	gyrA_1	CSACC_06640	CSACC_00070	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.598
dnaK_1	gyrA_2	CSACC_06640	CSACC_39720	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	DNA gyrase subunit A.	0.607
dnaK_1	parE	CSACC_06640	CSACC_39730	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	DNA topoisomerase 4 subunit B.	0.679
dnaK_2	dnaK_1	CSACC_06650	CSACC_06640	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.821
dnaK_2	gyrA_1	CSACC_06650	CSACC_00070	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.595
dnaK_2	gyrA_2	CSACC_06650	CSACC_39720	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	DNA gyrase subunit A.	0.585
dnaK_2	parE	CSACC_06650	CSACC_39730	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	DNA topoisomerase 4 subunit B.	0.667
dnaK_4	gyrA_1	CSACC_10780	CSACC_00070	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.626
dnaK_4	gyrA_2	CSACC_10780	CSACC_39720	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	DNA gyrase subunit A.	0.584
dnaK_4	parE	CSACC_10780	CSACC_39730	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	DNA topoisomerase 4 subunit B.	0.640
dnaN	gyrA_1	CSACC_00020	CSACC_00070	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.745
dnaN	parE	CSACC_00020	CSACC_39730	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA topoisomerase 4 subunit B.	0.697
dnaN	recF_1	CSACC_00020	CSACC_00040	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.	0.927
gyrA_1	dnaK_1	CSACC_00070	CSACC_06640	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.598
gyrA_1	dnaK_2	CSACC_00070	CSACC_06650	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	Chaperone protein DnaK; Belongs to the heat shock protein 70 family.	0.595
gyrA_1	dnaK_4	CSACC_00070	CSACC_10780	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.626
gyrA_1	dnaN	CSACC_00070	CSACC_00020	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.745
gyrA_1	gyrA_2	CSACC_00070	CSACC_39720	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	DNA gyrase subunit A.	0.589