STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sufS_2Cysteine desulfurase SufS. (379 aa)    
Predicted Functional Partners:
iscU
Iron-sulfur cluster assembly scaffold protein IscU.
  
 
 0.881
AQS01198.1
Hypothetical protein.
  
 
 0.854
AQR99704.1
Endonuclease/exonuclease/phosphatase family protein.
    
   0.646
YedF1
Hypothetical protein.
 
 
 
 0.634
YedF2
SirA-like protein; Belongs to the sulfur carrier protein TusA family.
 
 
 
 0.601
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.558
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.558
cdr_1
Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family.
   
 
 0.535
dnaJ_2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
   0.458
cysS
cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.434
Your Current Organism:
Clostridium saccharobutylicum
NCBI taxonomy Id: 169679
Other names: ATCC BAA-117, C. saccharobutylicum, Clostridium saccharobutylicum Keis et al. 2001, DSM 13864, strain NCP 262
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.