| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argG | guaB | CSACC_07150 | CSACC_03620 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.427 |
| argG | purA | CSACC_07150 | CSACC_45000 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.937 |
| argG | purL | CSACC_07150 | CSACC_12910 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Phosphoribosylformylglycinamidine synthase. | 0.611 |
| argG | pyrB | CSACC_07150 | CSACC_12400 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.912 |
| guaA | guaB | CSACC_03630 | CSACC_03620 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | hpt_1 | CSACC_03630 | CSACC_01370 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.958 |
| guaA | hpt_2 | CSACC_03630 | CSACC_11340 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.958 |
| guaA | purA | CSACC_03630 | CSACC_45000 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.967 |
| guaA | purB | CSACC_03630 | CSACC_14550 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.927 |
| guaA | purH_1 | CSACC_03630 | CSACC_12970 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Bifunctional purine biosynthesis protein PurH. | 0.885 |
| guaA | purH_2 | CSACC_03630 | CSACC_35810 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Bifunctional purine biosynthesis protein PurH. | 0.871 |
| guaA | purL | CSACC_03630 | CSACC_12910 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase. | 0.992 |
| guaA | pyrB | CSACC_03630 | CSACC_12400 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.775 |
| guaB | argG | CSACC_03620 | CSACC_07150 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.427 |
| guaB | guaA | CSACC_03620 | CSACC_03630 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | hpt_1 | CSACC_03620 | CSACC_01370 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.941 |
| guaB | hpt_2 | CSACC_03620 | CSACC_11340 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.941 |
| guaB | purA | CSACC_03620 | CSACC_45000 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.994 |
| guaB | purB | CSACC_03620 | CSACC_14550 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.919 |
| guaB | purH_1 | CSACC_03620 | CSACC_12970 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Bifunctional purine biosynthesis protein PurH. | 0.984 |