| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQS72644.1 | AQS73053.1 | CA40472_01060 | CA40472_03375 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.942 |
| AQS72644.1 | AQS73420.1 | CA40472_01060 | CA40472_05510 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Epoxyalkane--coenzyme M transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| AQS72644.1 | AQS73962.1 | CA40472_01060 | CA40472_08585 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.842 |
| AQS72644.1 | AQS74296.1 | CA40472_01060 | CA40472_10620 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.957 |
| AQS72644.1 | AQS74743.1 | CA40472_01060 | CA40472_04430 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
| AQS72644.1 | cysK | CA40472_01060 | CA40472_11060 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.847 |
| AQS72644.1 | ilvA | CA40472_01060 | CA40472_05525 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.816 |
| AQS72644.1 | luxS | CA40472_01060 | CA40472_10450 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.908 |
| AQS72644.1 | thrB | CA40472_01060 | CA40472_08580 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.846 |
| AQS73053.1 | AQS72644.1 | CA40472_03375 | CA40472_01060 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.942 |
| AQS73053.1 | AQS73420.1 | CA40472_03375 | CA40472_05510 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Epoxyalkane--coenzyme M transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
| AQS73053.1 | AQS73962.1 | CA40472_03375 | CA40472_08585 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |
| AQS73053.1 | AQS74296.1 | CA40472_03375 | CA40472_10620 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
| AQS73053.1 | AQS74743.1 | CA40472_03375 | CA40472_04430 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
| AQS73053.1 | cysK | CA40472_03375 | CA40472_11060 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.856 |
| AQS73053.1 | ilvA | CA40472_03375 | CA40472_05525 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.809 |
| AQS73053.1 | luxS | CA40472_03375 | CA40472_10450 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.905 |
| AQS73053.1 | metX | CA40472_03375 | CA40472_03370 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.998 |
| AQS73053.1 | thrB | CA40472_03375 | CA40472_08580 | O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.810 |
| AQS73420.1 | AQS72644.1 | CA40472_05510 | CA40472_01060 | Epoxyalkane--coenzyme M transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.900 |
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