| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQS72620.1 | AQS73178.1 | CA40472_00930 | CA40472_04095 | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AQS72620.1 | gcvP | CA40472_00930 | CA40472_05175 | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.956 |
| AQS72620.1 | glyA | CA40472_00930 | CA40472_09300 | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.926 |
| AQS73178.1 | AQS72620.1 | CA40472_04095 | CA40472_00930 | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AQS73178.1 | gcvP | CA40472_04095 | CA40472_05175 | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.913 |
| AQS73178.1 | gcvT | CA40472_04095 | CA40472_05170 | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.968 |
| AQS73178.1 | glyA | CA40472_04095 | CA40472_09300 | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
| gcvH | gcvP | CA40472_05155 | CA40472_05175 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.999 |
| gcvH | gcvT | CA40472_05155 | CA40472_05170 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvH | glyA | CA40472_05155 | CA40472_09300 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.968 |
| gcvH | kgd | CA40472_05155 | CA40472_08760 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.944 |
| gcvH | lpdA | CA40472_05155 | CA40472_02155 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
| gcvP | AQS72620.1 | CA40472_05175 | CA40472_00930 | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
| gcvP | AQS73178.1 | CA40472_05175 | CA40472_04095 | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
| gcvP | gcvH | CA40472_05175 | CA40472_05155 | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| gcvP | gcvT | CA40472_05175 | CA40472_05170 | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvP | glyA | CA40472_05175 | CA40472_09300 | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
| gcvP | guaA | CA40472_05175 | CA40472_03280 | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.909 |
| gcvP | kgd | CA40472_05175 | CA40472_08760 | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.965 |
| gcvP | lpdA | CA40472_05175 | CA40472_02155 | Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.971 |