STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lmo0540Lmo0540 protein; Similar to penicillin-binding protein. (397 aa)    
Predicted Functional Partners:
lmo0105
Lmo0105 protein; Highly similar to chitinase B.
     
 0.736
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
     
 0.706
lmo2754
Lmo2754 protein; Similar to D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
     
 0.699
lmo2781
Lmo2781 protein; Similar to beta-glucosidase.
 
 
 0.616
lmo1729
Lmo1729 protein; Similar to beta-glucosidases; Belongs to the glycosyl hydrolase 3 family.
 
 
 0.607
lmo1695
Phosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
   
 0.587
lmo2812
Lmo2812 protein; Similar to D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.569
lmo2229
Lmo2229 protein; Similar to penicillin-binding protein.
   
  
 0.554
dltB
DltB protein for D-alanine esterification of lipoteichoic acid and wall teichoic acid; Could be involved in the transport of activated D-alanine through the membrane.
 
  
 0.537
dltD
DltD protein for D-alanine esterification of lipoteichoic acid and wall teichoic acid.
  
 0.536
Your Current Organism:
Listeria monocytogenes
NCBI taxonomy Id: 169963
Other names: L. monocytogenes EGD-e, Listeria monocytogenes ATCC BAA-679, Listeria monocytogenes EGD-e, Listeria monocytogenes EGDe, Listeria monocytogenes str. EGD-e, Listeria monocytogenes strain EGD-e
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