lmo0794 protein (Listeria monocytogenes) - STRING interaction network

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second shell of interactors

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Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

lmo0794

Lmo0794 protein; Similar to B. subtilis YwnB protein. (213 aa)

Predicted Functional Partners:

lmo0134

0.909

lmo2573

0.885

lmo0554

0.875

lmo2391

0.864

lmo2748

0.864

lmo0539

0.860

lmo0169

0.856

lmo2158

0.855

lmo0913

0.847

lmo0133

0.846

Your Current Organism:

Listeria monocytogenes

NCBI taxonomy Id: 169963
Other names: L. monocytogenes EGD-e, Listeria monocytogenes ATCC BAA-679, Listeria monocytogenes EGD-e, Listeria monocytogenes EGDe, Listeria monocytogenes str. EGD-e, Listeria monocytogenes strain EGD-e

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
lmo0133	lmo0134	gene:17592769	gene:17592770	Lmo0133 protein; Similar to E. coli YjdI protein.	Lmo0134 protein; Similar to E. coli YjdJ protein.	0.998
lmo0133	lmo0169	gene:17592769	gene:17592805	Lmo0133 protein; Similar to E. coli YjdI protein.	Putative sugar uptake protein lmo0169; Similar to a glucose uptake protein.	0.625
lmo0133	lmo0539	gene:17592769	gene:17593190	Lmo0133 protein; Similar to E. coli YjdI protein.	Similar to tagatose-1,6-diphosphate aldolase; Belongs to the aldolase LacD family.	0.543
lmo0133	lmo0794	gene:17592769	gene:17593445	Lmo0133 protein; Similar to E. coli YjdI protein.	Lmo0794 protein; Similar to B. subtilis YwnB protein.	0.846
lmo0133	lmo0913	gene:17592769	gene:17593568	Lmo0133 protein; Similar to E. coli YjdI protein.	Similar to succinate semialdehyde dehydrogenase.	0.667
lmo0133	lmo2158	gene:17592769	gene:17594849	Lmo0133 protein; Similar to E. coli YjdI protein.	Similar to B. subtilis YwmG protein.	0.710
lmo0133	lmo2391	gene:17592769	gene:17595101	Lmo0133 protein; Similar to E. coli YjdI protein.	Conserved hypothetical protein similar to B. subtilis YhfK protein.	0.821
lmo0133	lmo2573	gene:17592769	gene:17595284	Lmo0133 protein; Similar to E. coli YjdI protein.	Zinc-type alcohol dehydrogenase-like protein; Similar to zinc-binding dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.	0.817
lmo0133	lmo2748	gene:17592769	gene:17595465	Lmo0133 protein; Similar to E. coli YjdI protein.	Lmo2748 protein; Similar to B. subtilis stress protein YdaG.	0.812
lmo0134	lmo0133	gene:17592770	gene:17592769	Lmo0134 protein; Similar to E. coli YjdJ protein.	Lmo0133 protein; Similar to E. coli YjdI protein.	0.998
lmo0134	lmo0169	gene:17592770	gene:17592805	Lmo0134 protein; Similar to E. coli YjdJ protein.	Putative sugar uptake protein lmo0169; Similar to a glucose uptake protein.	0.795
lmo0134	lmo0539	gene:17592770	gene:17593190	Lmo0134 protein; Similar to E. coli YjdJ protein.	Similar to tagatose-1,6-diphosphate aldolase; Belongs to the aldolase LacD family.	0.874
lmo0134	lmo0554	gene:17592770	gene:17593205	Lmo0134 protein; Similar to E. coli YjdJ protein.	Lmo0554 protein; Similar to NADH-dependent butanol dehydrogenase.	0.861
lmo0134	lmo0794	gene:17592770	gene:17593445	Lmo0134 protein; Similar to E. coli YjdJ protein.	Lmo0794 protein; Similar to B. subtilis YwnB protein.	0.909
lmo0134	lmo0913	gene:17592770	gene:17593568	Lmo0134 protein; Similar to E. coli YjdJ protein.	Similar to succinate semialdehyde dehydrogenase.	0.823
lmo0134	lmo2158	gene:17592770	gene:17594849	Lmo0134 protein; Similar to E. coli YjdJ protein.	Similar to B. subtilis YwmG protein.	0.875
lmo0134	lmo2391	gene:17592770	gene:17595101	Lmo0134 protein; Similar to E. coli YjdJ protein.	Conserved hypothetical protein similar to B. subtilis YhfK protein.	0.825
lmo0134	lmo2573	gene:17592770	gene:17595284	Lmo0134 protein; Similar to E. coli YjdJ protein.	Zinc-type alcohol dehydrogenase-like protein; Similar to zinc-binding dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.	0.828
lmo0134	lmo2748	gene:17592770	gene:17595465	Lmo0134 protein; Similar to E. coli YjdJ protein.	Lmo2748 protein; Similar to B. subtilis stress protein YdaG.	0.866
lmo0169	lmo0133	gene:17592805	gene:17592769	Putative sugar uptake protein lmo0169; Similar to a glucose uptake protein.	Lmo0133 protein; Similar to E. coli YjdI protein.	0.625

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006457

Protein folding

8 of 251

1.77

3.45

4.00e-10

GO:0042026

Protein refolding

4 of 47

2.2

2.36

2.32e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031072

Heat shock protein binding

8 of 67

2.34

6.52

7.23e-15

GO:0030544

Hsp70 protein binding

6 of 22

2.7

6.19

1.12e-12

GO:0051082

Unfolded protein binding

8 of 125

2.07

5.15

4.16e-13

GO:0051087

Chaperone binding

6 of 47

2.37

5.03

5.09e-11

GO:0005515

Protein binding

9 of 2044

0.91

1.85e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005788

Endoplasmic reticulum lumen

5 of 25

2.57

4.53

1.81e-09

GO:0034663

Endoplasmic reticulum chaperone complex

2 of 2

3.27

1.77

0.00064

GO:0005783

Endoplasmic reticulum

6 of 910

1.09

0.94

0.00083

GO:0099503

Secretory vesicle

2 of 53

1.84

0.74

0.0392

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12131

ATP-dependent protein folding chaperone, and DnaJ domain, conserved site

7 of 61

2.33

5.42

3.88e-12

CL:12219

Mixed, incl. Hsp70 protein binding, and LRAT domain

5 of 17

2.74

5.22

1.22e-10

CL:12699

Endoplasmic reticulum chaperone complex, and Calreticulin

3 of 5

3.05

3.22

1.36e-06

CL:12241

Mixed, incl. LRAT domain, and DnaJ C terminal domain

3 of 6

2.97

3.13

1.93e-06

CL:12220

Mixed, incl. Hsp70 protein binding, and MreB/Mbl protein

2 of 11

2.53

1.37

0.0030

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04141

Protein processing in endoplasmic reticulum

10 of 324

1.76

4.45

1.99e-15

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-3371497

HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand

5 of 37

2.4

4.02

1.09e-08

MAP-2262752

Cellular responses to stress

8 of 515

1.46

2.33

1.13e-08

MAP-8953897

Cellular responses to stimuli

8 of 517

1.46

2.32

1.13e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034663

Endoplasmic reticulum chaperone complex

2 of 9

2.61

0.96

0.0177

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00684

DnaJ central domain

2 of 9

2.61

0.87

0.0264

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR018253

DnaJ domain, conserved site

7 of 38

2.53

6.25

2.76e-13

IPR001623

DnaJ domain

7 of 84

2.19

4.83

2.44e-11

IPR036869

Chaperone J-domain superfamily

7 of 90

2.16

4.76

2.58e-11

IPR008971

HSP40/DnaJ peptide-binding

3 of 16

2.54

2.06

0.00015

IPR002939

Chaperone DnaJ, C-terminal

3 of 16

2.54

2.06

0.00015

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00271

DnaJ molecular chaperone homology domain

7 of 87

2.17

5.04

5.46e-12

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