node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysK | hom | gene:17592859 | gene:17595258 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Highly similar to homoserine dehydrogenase. | 0.640 |
cysK | ilvA | gene:17592859 | gene:17594676 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.654 |
cysK | lmo0595 | gene:17592859 | gene:17593246 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Lmo0595 protein; Similar to O-acetylhomoserine sulfhydrylase. | 0.938 |
cysK | lmo0845 | gene:17592859 | gene:17593496 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Lmo0845 protein; Similar to B. subtilis YxjH and YxjG proteins. | 0.896 |
cysK | lmo1288 | gene:17592859 | gene:17593945 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.950 |
cysK | lmo1494 | gene:17592859 | gene:17594151 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.536 |
cysK | lmo1678 | gene:17592859 | gene:17594335 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Lmo1678 protein; Similar to 5-methyltetrahydrofolate-homocysteine methyltransferase (metH). | 0.954 |
cysK | lmo1679 | gene:17592859 | gene:17594336 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Lmo1679 protein; Similar to cystathionine beta-lyase. | 0.985 |
cysK | lmo1680 | gene:17592859 | gene:17594337 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Lmo1680 protein; Similar to cystathionine gamma-synthase. | 0.985 |
cysK | lmo1681 | gene:17592859 | gene:17594338 | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.914 |
hom | cysK | gene:17595258 | gene:17592859 | Highly similar to homoserine dehydrogenase. | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.640 |
hom | ilvA | gene:17595258 | gene:17594676 | Highly similar to homoserine dehydrogenase. | L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.821 |
hom | lmo0595 | gene:17595258 | gene:17593246 | Highly similar to homoserine dehydrogenase. | Lmo0595 protein; Similar to O-acetylhomoserine sulfhydrylase. | 0.943 |
hom | lmo0845 | gene:17595258 | gene:17593496 | Highly similar to homoserine dehydrogenase. | Lmo0845 protein; Similar to B. subtilis YxjH and YxjG proteins. | 0.918 |
hom | lmo1288 | gene:17595258 | gene:17593945 | Highly similar to homoserine dehydrogenase. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.902 |
hom | lmo1678 | gene:17595258 | gene:17594335 | Highly similar to homoserine dehydrogenase. | Lmo1678 protein; Similar to 5-methyltetrahydrofolate-homocysteine methyltransferase (metH). | 0.985 |
hom | lmo1679 | gene:17595258 | gene:17594336 | Highly similar to homoserine dehydrogenase. | Lmo1679 protein; Similar to cystathionine beta-lyase. | 0.933 |
hom | lmo1680 | gene:17595258 | gene:17594337 | Highly similar to homoserine dehydrogenase. | Lmo1680 protein; Similar to cystathionine gamma-synthase. | 0.933 |
hom | lmo1681 | gene:17595258 | gene:17594338 | Highly similar to homoserine dehydrogenase. | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.928 |
ilvA | cysK | gene:17594676 | gene:17592859 | L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Highly similar to cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.654 |