STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxAThioredoxin; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). (103 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase.
 0.997
lmo2390
Ferredoxin--NADP reductase 2; Similar to hypothetical thioredoxine reductase.
 
 0.889
lmo1961
Ferredoxin--NADP reductase 1; Similar to oxidoreductases.
 
 0.794
mecA
Competence negative regulator mecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
   
    0.754
groEL
Class I heat-shock protein (chaperonin) GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.723
fus
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.698
lmo0689
Lmo0689 protein; Similar to CheA activity-modulating chemotaxis protein CheV.
  
 0.689
lmo1734
Lmo1734 protein; Similar to glutamate synthase (large subunit).
  
 
 0.685
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
 
 0.682
nifJ
NifJ protein; Highly similar to pyruvate-flavodoxin oxidoreductase.
    
 0.675
Your Current Organism:
Listeria monocytogenes
NCBI taxonomy Id: 169963
Other names: L. monocytogenes EGD-e, Listeria monocytogenes ATCC BAA-679, Listeria monocytogenes EGD-e, Listeria monocytogenes EGDe, Listeria monocytogenes str. EGD-e, Listeria monocytogenes strain EGD-e
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