STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdc6-2ORC1-type DNA replication protein 2; Involved in regulation of DNA replication. (401 aa)    
Predicted Functional Partners:
mcm
Minichromosome maintenance protein MCM.
 
 0.993
priL
DNA primase large subunit PriL; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
 0.952
priS
DNA primase small subunit PriS; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthe [...]
 
 
 0.927
dpo1
DNA polymerase 1.
 
 0.900
pol_2
DNA polymerase.
  
 0.866
pol_4
DNA polymerase.
  
 0.864
AOA65_0812
Single-stranded DNA-binding protein.
 
 
 0.855
AOA65_1252
Single-stranded DNA-binding protein.
 
 
 0.835
rpa_1
Replication factor A.
 
 
 0.832
AOA65_1315
Bacterial regulatory protein, arsR family.
       0.824
Your Current Organism:
Bathyarchaeota archaeon BA1
NCBI taxonomy Id: 1700835
Other names: C. Bathyarchaeota archaeon BA1, Candidatus Bathyarchaeota archaeon BA1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.