STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMK53136.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
 0.999
mutS
dNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
   
 0.996
mutL
Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 0.996
dnaA
Hypothetical protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 0.985
AMK54137.1
DNA-dirted DNA polymerase; 'Pfam: OB-fold nucleic acid binding domain; Pfam: Bacterial DNA polymerase III alpha subunit; TIGRFAM: polc: DNA polymerase III, alpha subunit; Pfam: PHP domain; Pfam: Helix-hairpin-helix motif'.
  
 
 0.985
AMK54197.1
'Pfam: DNA polymerase III, delta subunit; TIGRFAM: holA: DNA polymerase III, delta subunit'.
 
 
 0.984
dnaX
DNA-dirted DNA polymerase; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.978
AMK53162.1
Hypothetical protein; 'Pfam: DNA polymerase III, delta subunit'.
 
 
 0.974
AMK54149.1
Hypothetical protein; Pfam: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: xth: exodeoxyribonuclease III (xth); TIGRFAM: exoDNase_III: exodeoxyribonuclease III.
  
 0.950
AMK55739.1
ATPase of the AAA+ class; SMART: ATPases associated with a variety of cellular activities; PRINTS: CbxX/CfqX protein signature; PRINTS: CbxX/CfqX superfamily signature; Pfam: ATPase family associated with various cellular activities (AAA).
  
 
 0.934
Your Current Organism:
Faecalibaculum rodentium
NCBI taxonomy Id: 1702221
Other names: Allobaculum sp. Alo17, Erysipelotrichaceae bacterium Alo17, F. rodentium, Faecalibaculum rodentium Chang et al. 2016 emend. Cox et al. 2017, JCM 30274, KCTC 15484, strain ALO17
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