STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa)    
Predicted Functional Partners:
AMK53319.1
'Pfam: Anthranilate synthase component I, N terminal region; PRINTS: Anthranilate synthase component I signature; Pfam: chorismate binding enzyme'.
 0.999
AMK53320.1
Anthranilate synthase subunit II; PRINTS: Glutamine amidotransferase superfamily signature; PRINTS: Anthranilate synthase component II signature; TIGRFAM: trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; Pfam: Glutamine amidotransferase class-I; PRINTS: Carbamoyl-phosphate synthase protein GATase domain signature.
 
 0.999
trpC
Pfam: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
 0.999
trpF
Pfam: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family.
 
 
 0.999
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.994
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.988
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
      0.675
AMK54830.1
Histidinol-phosphate transaminase; Pfam: Aminotransferase class I and II.
  
  
 0.644
hisE
Pfam: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: histidine_hisI: phosphoribosyl-ATP diphosphatase.
  
  
 0.641
AMK55714.1
Prephenate dehydratase; Pfam: Chorismate mutase type II; SMART: Chorismate mutase type II; Pfam: Prephenate dehydratase.
 
  
 0.600
Your Current Organism:
Faecalibaculum rodentium
NCBI taxonomy Id: 1702221
Other names: Allobaculum sp. Alo17, Erysipelotrichaceae bacterium Alo17, F. rodentium, Faecalibaculum rodentium Chang et al. 2016 emend. Cox et al. 2017, JCM 30274, KCTC 15484, strain ALO17
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