Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMK53167.1 | fhs | AALO17_00330 | AALO17_00690 | Hypothetical protein; 'Pfam: CobB/CobQ-like glutamine amidotransferase domain; Pfam: AIR synthase related protein, N-terminal domain; Pfam: AIR synthase related protein, C-terminal domain; TIGRFAM: FGAM-synthase: phosphoribosylformylglycinamidine synthase'. | Pfam: Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.972 |
| AMK53167.1 | folD | AALO17_00330 | AALO17_04970 | Hypothetical protein; 'Pfam: CobB/CobQ-like glutamine amidotransferase domain; Pfam: AIR synthase related protein, N-terminal domain; Pfam: AIR synthase related protein, C-terminal domain; TIGRFAM: FGAM-synthase: phosphoribosylformylglycinamidine synthase'. | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.753 |
| AMK53167.1 | glyA | AALO17_00330 | AALO17_04870 | Hypothetical protein; 'Pfam: CobB/CobQ-like glutamine amidotransferase domain; Pfam: AIR synthase related protein, N-terminal domain; Pfam: AIR synthase related protein, C-terminal domain; TIGRFAM: FGAM-synthase: phosphoribosylformylglycinamidine synthase'. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.968 |
| AMK53167.1 | purH | AALO17_00330 | AALO17_00370 | Hypothetical protein; 'Pfam: CobB/CobQ-like glutamine amidotransferase domain; Pfam: AIR synthase related protein, N-terminal domain; Pfam: AIR synthase related protein, C-terminal domain; TIGRFAM: FGAM-synthase: phosphoribosylformylglycinamidine synthase'. | IMP cyclohydrolase; SMART: MGS-like domain; Pfam: MGS-like domain; SMART: AICARFT/IMPCHase bienzyme; Pfam: AICARFT/IMPCHase bienzyme; TIGRFAM: purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.993 |
| AMK53167.1 | purN | AALO17_00330 | AALO17_00360 | Hypothetical protein; 'Pfam: CobB/CobQ-like glutamine amidotransferase domain; Pfam: AIR synthase related protein, N-terminal domain; Pfam: AIR synthase related protein, C-terminal domain; TIGRFAM: FGAM-synthase: phosphoribosylformylglycinamidine synthase'. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
| AMK53656.1 | AMK55506.1 | AALO17_05220 | AALO17_23720 | L-serine ammonia-lyase; Pfam: Serine dehydratase alpha chain; Pfam: Serine dehydratase beta chain. | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.933 |
| AMK53656.1 | glyA | AALO17_05220 | AALO17_04870 | L-serine ammonia-lyase; Pfam: Serine dehydratase alpha chain; Pfam: Serine dehydratase beta chain. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.961 |
| AMK54329.1 | AMK55506.1 | AALO17_11950 | AALO17_23720 | L-threonine aldolase; Pfam: Beta-eliminating lyase. | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.934 |
| AMK54329.1 | glyA | AALO17_11950 | AALO17_04870 | L-threonine aldolase; Pfam: Beta-eliminating lyase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.936 |
| AMK54795.1 | AMK55506.1 | AALO17_16610 | AALO17_23720 | Hypothetical protein; Pfam: Methylenetetrahydrofolate reductase; Pfam: Homocysteine S-methyltransferase. | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.890 |
| AMK54795.1 | fhs | AALO17_16610 | AALO17_00690 | Hypothetical protein; Pfam: Methylenetetrahydrofolate reductase; Pfam: Homocysteine S-methyltransferase. | Pfam: Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.949 |
| AMK54795.1 | folD | AALO17_16610 | AALO17_04970 | Hypothetical protein; Pfam: Methylenetetrahydrofolate reductase; Pfam: Homocysteine S-methyltransferase. | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.944 |
| AMK54795.1 | glyA | AALO17_16610 | AALO17_04870 | Hypothetical protein; Pfam: Methylenetetrahydrofolate reductase; Pfam: Homocysteine S-methyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.957 |
| AMK54795.1 | purH | AALO17_16610 | AALO17_00370 | Hypothetical protein; Pfam: Methylenetetrahydrofolate reductase; Pfam: Homocysteine S-methyltransferase. | IMP cyclohydrolase; SMART: MGS-like domain; Pfam: MGS-like domain; SMART: AICARFT/IMPCHase bienzyme; Pfam: AICARFT/IMPCHase bienzyme; TIGRFAM: purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.940 |
| AMK54795.1 | purN | AALO17_16610 | AALO17_00360 | Hypothetical protein; Pfam: Methylenetetrahydrofolate reductase; Pfam: Homocysteine S-methyltransferase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.938 |
| AMK54795.1 | thyA | AALO17_16610 | AALO17_16840 | Hypothetical protein; Pfam: Methylenetetrahydrofolate reductase; Pfam: Homocysteine S-methyltransferase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.937 |
| AMK55506.1 | AMK53656.1 | AALO17_23720 | AALO17_05220 | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-serine ammonia-lyase; Pfam: Serine dehydratase alpha chain; Pfam: Serine dehydratase beta chain. | 0.933 |
| AMK55506.1 | AMK54329.1 | AALO17_23720 | AALO17_11950 | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-threonine aldolase; Pfam: Beta-eliminating lyase. | 0.934 |
| AMK55506.1 | AMK54795.1 | AALO17_23720 | AALO17_16610 | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Hypothetical protein; Pfam: Methylenetetrahydrofolate reductase; Pfam: Homocysteine S-methyltransferase. | 0.890 |
| AMK55506.1 | glyA | AALO17_23720 | AALO17_04870 | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.932 |
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